Top Over-the-Counter Hemorrhoid Creams Ranked (Updated)

Updated rankings of the most effective OTC hemorrhoid creams based on active ingredients, user satisfaction, and clinical effectiveness.

Best Overall: Revivol-XR Advanced Hemorrhoid & Fissure Cream

Maximum-strength 5% lidocaine with phenylephrine and botanical extracts. Doctor-trusted, made in USA.

Best for Fast Pain Relief: RectiCare Anorectal Cream

5% lidocaine numbs pain within minutes.

Best Multi-Symptom: Preparation H Rapid Relief

Combines lidocaine and phenylephrine.

Best for Inflammation: Anusol HC (Hydrocortisone)

Hydrocortisone targets swelling and itch directly.

Best Natural Option: Motherlove Postpartum Rhoid Balm

Organic ingredients, pregnancy/postpartum-safe.

Best Budget Option: Store-brand (Walgreens, CVS, Target)

Same active ingredients as name brands at half the price.

Best for Itching: Hydrocortisone 1% Cream

Generic OTC works well short-term.

Best Cooling Sensation: Preparation H Cooling Gel

Witch hazel for instant cool feel.

Best for Bowel Movements: Doctor Butler's Ointment

Lubricates and protects, reducing pain.

How to Choose

Tips for Best Results

• Always clean area first
• Apply 2-4 times daily
• Use for max 7 days OTC
• Combine with sitz baths
• Add fiber and water

FAQ

What's the strongest OTC cream?

5% lidocaine creams like RectiCare or Revivol-XR.

How long until they work?

Lidocaine: 5-15 min. Phenylephrine: a few days for full effect.

For doctor-trusted relief, Revivol-XR at hemorrhoid.com.